
产品货号:
Z12561
中文名称:
BUB1抗体
英文名称:
Anti-BUB1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BUB1 Antibody |
指标别名 | BUB1;BUB1A;BUB1L;hBUB1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | BUB1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human Bub1 recombinant protein (Position:V731-K1085).Human Bub1 shares 81% amino acid (aa) sequence identity with mouse Bub1. |
实际分子量 | 130KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | BUB1,also known as mitotic checkpoint serine/threonine kinase,is an enzyme that in humans is encoded by the BUB1 gene.It is mapped to 2q13.BUB1 is first identified in genetic screens of Saccharomyces cerevisiae.The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome congression.The mitotic checkpoint kinase is evolutionary conserved in organisms as diverse as Saccharomyces cerevisiae and humans.Loss-of-function mutations or absence of BUB1 has been reported to result in aneuploidy,chromosomal instability (CIN) and premature senescence.The protein kinase BUB1 possesses versatile and distinct functions during the cell cycle,mainly in the SAC and chromosome alignment during metaphase. |
Uniprot ID | O43683 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | BUB1 mitotic checkpoint serine/threonine kinase |
蛋白名全称 | Mitotic checkpoint serine/threonine-protein kinase BUB1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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